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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

Question 1

Which virus is recognized as the leading cause of sporadic, severe gastroenteritis in infants and young children globally, for which effective vaccines are now available?

A. Enteric Adenovirus (serotypes 40, 41)
B. Astrovirus
C. Rotavirus
D. Norovirus

Question 2

A patient who received a solid organ transplant develops a pneumonia. Bronchoalveolar lavage fluid is positive for a single-stranded RNA virus that can cause giant cell formation with intranuclear and intracytoplasmic inclusions. The MOST likely causative agent is:

A. Adenovirus
B. Parainfluenza virus
C. Respiratory syncytial virus (RSV)
D. Human metapneumovirus

Question 3

In a clinical microbiology laboratory, quality control testing of Mueller-Hinton agar used for disk diffusion susceptibility testing involves checking the zone sizes for E. coli ATCC 25922, S. aureus ATCC 25923, and
P. aeruginosa ATCC 27853. What is the primary purpose of including P. aeruginosa ATCC 27853 in this QC?

A. To assess the performance of agents primarily active against Gram-positive organisms
B. To confirm the correct pH of the agar medium
C. To verify the performance of cell wall active agents like penicillin
D. To ensure appropriate concentration of calcium and magnesium ions affecting aminoglycoside activity

Question 4

A patient with a history of inflammatory bowel disease is diagnosed with primary sclerosing cholangitis and undergoes liver transplantation. Post-transplant, they develop a bloodstream infection with a Gram-negative bacterium that is identified as Fusobacterium nucleatum. This organism's role in the pathogenesis of colorectal cancer is primarily attributed to its ability to:

A. Form biofilms that physically obstruct the bile ducts.
B. Produce potent exotoxins that damage the intestinal epithelium.
C. Directly induce mutations in colonic epithelial cells.
D. Modulate the host immune response and promote a pro-inflammatory microenvironment.

Question 5

A patient with a history of solid organ transplantation develops a severe respiratory illness. Bronchoalveolar lavage fluid is positive for cytomegalovirus (CMV) DNA by PCR, and cytological examination reveals characteristic "owl's eye" inclusions in enlarged cells. The MOST appropriate management strategy for this patient would include:

A. Initiation of broad-spectrum antibiotics to cover potential bacterial coinfections.
B. Treatment with antiviral agents such as ganciclovir or valganciclovir.
C. Supportive care and monitoring for spontaneous resolution.
D. Administration of corticosteroids to reduce inflammation.

Solutions: